Combos Utilizing Urza-sq-s-Guilt

lay the megrim down first turn with dark ritual. then second turn lay a stormscape familiar. third turn lay a mirari with a dark ritual. then just stall till you can play guilt and mirari it.

You will lose 4 life, anyway, you opponent will take no less than eight damage, granted he has more than 2 cards to pitch. Great combo, easy 4, 5 turn win...

You deal 10 damage with 4 mana with both cards.

Megrim+Guilt for 10. Yawgmoth's Agenda the Guilt for 10 more= GAME!

Play Megrim on your 3rd turn, play Breathstealer's Crypt on your 4th turn, play another Megrim on your 5th turn, play Urza's Guilt on your 6th turn. 20 point combo is possible.

use with bounce cards when your opp. runs out of a hand

have both enchantments in play. cast guilt. opponent must draw 2 cards & lose 8 life. you can choose whether to draw cards or not

play the tyranny and the megrim, cast guilt, they take four from the guilt, six from the megrim and four from the tyranny !! bang game over

When the other player plays a spell, they take two damage and discard a card. With Urza's Guilt the other player discards three for six damage and then lose four life.