Combos Utilizing Despotic-Scepter

use the can, then before it is removed from the game, bury it

cast mutation destroy opponent's artifact. put 1/1tokens into play (equal to artifact's converted mana cost). cast cultural & exchange tokens for opponent's creatures. tap scepter-destroy a token

destroy land with scepter to keep you with less land in play than opponent. draw 3 land each turn with land tax & discard them to land's edge for 6 damage to opponent

whatever permanent opponent plays that was removed by shared fate gets destroyed by despotic scepter for 1 colorless

take control of opponents creature until end of turn with the overtaker, then attack them with it, then use the sceptor to destroy the creature before it goes back to them.

"if i can't have karona, no one will! bwahahahahahaha! ;-)"

cast mutation return opponent's creature to his hand. put 1/1tokens into play (= to returned creature's mana cost). cast cultural & exchange tokens for opponent's creatures. tap scepter-destroy token

Infinite life/mana.Requires massive stack manipulation. Pay life for channel, life gain goes on stack. Let some resolve, pay more life. Destroy Transcendence when you have enough life on stack and mana in pool. Then Fireball for infinity or something

put custody battle on opponent's creature. once you get control of it, tap scepter to destroy custody battle

cast mutation destroy opponent's enchantment. put 1/1tokens into play (= to enchantment's converted mana cost). cast cultural & exchange tokens for opponent's creatures. tap scepter-destroy a token